Handguns/Pistols | Semi-AutomaticGlockSold by Sportsmans Guide

Glock

Glock 21 V MOS .45 ACP 4.61" Barrel Optic Ready Front Serrations 13+1 Rounds

Our editorial team reviews specifications, product data, and field-use information to keep pages accurate.

Full-size Glock

21 V MOS chambered in

Factory Mos

Slide is optic-ready for popular

Includes One

Adapter plate; additional plates sold

4.61-inch Glock

Marksman Barrel with enhanced rifling

Front Serrations

Support press checks

$620.00
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SKU: WX2*0749368

Overview

Built for shooters who want a full-size .45 ACP pistol with modern optic-ready flexibility, this model pairs a factory MOS slide with a 4.61" Glock Marksman Barrel and a 13+1 capacity. It is suited to duty use, home defense, and tactical roles, with features such as front serrations, ambidextrous slide stop levers, a flared magwell, and no finger grooves for a more universal fit. The included adapter plate makes it easy to start mounting a miniature red dot sight, while additional plates can be added separately to match your preferred optic. Glock’s SAFE ACTION System and full-size frame round out a practical platform for shooters who value straightforward operation and control.

Why Hunters Choose the Glock

Factory Mos

Slide is optic-ready for popular

Includes One

Adapter plate to start mounting

4.61-inch Glock

Marksman Barrel features enhanced rifling

Full-size Frame

Longer barrel support better recoil

13+1 Capacity

Three included 13-round magazines

Key Features

  • Full-size Glock 21 V MOS chambered in .45 ACP with 13+1 capacity
  • Factory MOS slide is optic-ready for popular miniature red dot sights
  • Includes one adapter plate; additional plates sold separately
  • 4.61-inch Glock Marksman Barrel with enhanced rifling
  • Front serrations support press checks
  • Ambidextrous slide stop levers and reversible magazine catch
  • Flared magwell and no finger grooves for a more universal fit

Best Used For

  • Home defense users wanting a full-size .45 ACP pistol with optic-ready capability.
  • Duty or tactical shooters who prefer red dot mounting without custom slide milling.
  • Hunters needing a controllable sidearm with a full-size frame and 13+1 capacity.
  • Shooters who value ambidextrous controls and a universal-fit grip profile.
  • Users seeking a factory-configured pistol for faster target acquisition and reloads.

Specifications

Ambidextrous Slide Stop LeversYes
Barrel Length4.61 inches
Barrel TypeGlock Marksman Barrel
Blade FinishMatte black
Caliber.45 ACP
Capacity13+1 rounds
ErgonomicsRefined ergonomics
Flared MagwellYes
Frame SizeFull-size
Front SerrationsYes
Included Adapter Plates1
Included Magazines3 x 13-round magazines
Mos SystemYes
No Finger GroovesYes
Optic ReadyYes
Reversible Magazine CatchYes
RiflingEnhanced rifling
Safety SystemSAFE ACTION System

Pros

  • Factory MOS slide is optic-ready for popular miniature red dot sights.
  • Includes one adapter plate to start mounting compatible optics.
  • 4.61-inch Glock Marksman Barrel features enhanced rifling for improved accuracy.
  • Full-size frame and longer barrel support better recoil control.
  • 13+1 capacity with three included 13-round magazines.
  • Front serrations, flared magwell, and ambidextrous slide stop levers add practical handling features.

Considerations & Trade-offs

  • Full-size frame and 13+1 capacity make it less compact for concealed carry or minimalist setups.
  • Optic-ready use is limited to compatible miniature red dot sights and the included adapter plate; additional plates are sold separately.
  • The .45 ACP chambering offers substantial power, but it also means higher recoil and typically larger ammunition than smaller-caliber alternatives.
  • The pistol includes three 13-round magazines, so users wanting a different carry or range setup may need to source additional magazines separately.

Suggested Comparisons

  • Full-size .45 ACP pistol
  • Optic-ready handgun
  • Home defense pistol
  • Duty/tactical pistol

Suggested Accessories

  • Optic mount adapter plate
  • Miniature red dot sight
  • Pistol cleaning kit
  • Magazine pouch

Frequently Asked Questions

Is the Glock 21 V MOS optic ready from the factory?

Yes. The MOS (Modular Optic System) slide is precision-machined for red dot mounting, and the pistol includes one adapter plate to get started. Additional adapter plates are sold separately.

What caliber and capacity does this model use?

It is chambered in .45 ACP and listed with 13+1 capacity. The product also includes three 13-round magazines.

What barrel length is listed for the Glock 21 V MOS?

The listed barrel length is 4.61 inches. The description identifies it as a Glock Marksman Barrel with enhanced rifling.

Does the slide have features that help with handling and checks?

Yes. The product lists front serrations for press checks, along with ambidextrous slide stop levers.

What comes in the box?

The listing states that the pistol includes one adapter plate and three 13-round magazines. It also notes that additional adapter plates are sold separately.